ASTM ISO/ASTM 51939 Standard Practice for Blood Irradiation Dosimetry

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ASTM ISO/ASTM 51939 Document Information:

Title
Standard Practice for Blood Irradiation Dosimetry

ASTM International

Publication Date:
Jan 1, 2005

Scope:

This practice outlines irradiator installation qualification, operational qualification, performance qualification, and routine product processing dosimetric procedures to be followed in the irradiation of blood and blood components by the blood-banking community. If followed, these procedures will help to ensure that the products processed with ionizing radiation from gamma, X-rays (bremsstrahlung), or electron sources receive absorbed doses within a predetermined range.

This practice covers dosimetry for the irradiation of blood for these types of irradiators: self-contained irradiators (free-standing irradiators) utilizing ¹³⁷Cs, ⁶⁰Co or X-rays (bremsstrahlung), teletherapy units, and electron accelerators. The absorbed dose range for blood irradiation is typically 15 Gy to 50 Gy. In some jurisdictions, the absorbed dose range for blood irradiation is 25 Gy to 50 Gy.

The energy range is typically from approximately 40 keV to 5 MeV for photons, and up to 10 MeV for electrons.

This practice also covers the use of radiation-sensitive indicators for the visual and qualitative indication that the product has been irradiated.

This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and to determine the applicability or regulatory limitations prior to use.

Keywords:

absorbed-dose mapping

blood and blood products

measurement quality assurance plan

blood irradiation

measurement uncertainty

ionizing radiation

ICS 17.240

absorbed dose

transfer-standard dosimeter

routine dosimeter

dosimeter

radiation-sensitive indicators

irradiator

reference-standard dosimeter

dosimetry system

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